Description: The use of fundamental techniques in molecular biology and molecular genetics are illustrated using examples from the classic and current literature. Selected topics include eukaryotic gene cloning, transgenic animals, rational drug design, DNA replication and cell cycle regulation.
Description: Topics to be considered at an advanced level will include: translation, folding and assembly, targeting, turnover, structure and motifs.
Microbiology and immunology 4750
Description: An overview of concepts and applications of techniques in bioinformatics for the study and clinical/public health management of infectious diseases. Students are introduced to the basic analysis of conventional and next-generation sequence data, principles of maximum likelihood and Bayesian inference, reconstructing epidemic and evolutionary histories, detecting adaptation, and molecular epidemiology.
Description: The major laboratory course for the Honors Specialization in Biochemistry and Honors Specialization modules combined with Biochemistry. Lectures on laboratory safety, biosafety, use of animals in research, scientific integrity; an independent research project (topic and advisor chosen by consultation between student and faculty); scientific communication (two seminars and a written report).